Papers

AI-based HIV-1 Env designs devoid of gp41 mimic native gp120 pre-fusion Env In preparation

Aldon Y^*, Jo G^*, Jasti N, Kim YJ, Allen JD, Bouhuijs JH, Tran A, Skotheim RK, Juergens D, Koo JH, Parikh S, Snitselaar JL, Olijhoek WW, de Gast M, Langowski M, Fries C, Atabey T, van Breemen MJ, van Gils MJ, Crispin M, Ozorowski G, Batista FD, Ward AB, Baker D, Sanders RW^#, King NP^#

In preparation.

Structural and genetic basis of influenza hemagglutinin anchor epitope recognition guides antibody and immunogen design Under review

Swanson OM, Jo G, Clark J, Okba N, Loeffler JR, Copps J, Rodriguez AJ, Ferguson J, Raghavan SSR, Guthmiller JJ, Krammer F, Ward AB^#, Fernández Quintero ML^#, Han J^#

Under review.

Serum IgA proteomics reveals clonal composition and neutralization of dimeric and monomeric IgA repertoires against human norovirus

Park J^*, Jo G^*, Reyes Y^*, Pickens W, Kim DS, Beaver A, Costantini VP, Liu C, Kim D, Park D, Longo V, Brewer-Jensen PD, Mallory ML, Satterwhite E, Zapata-Bustos R, Marchioni J, Zweigart MR, Flitter BA, Vinjé J, Han J, Ross TM, Lee J, Lavinder JJ, Tucker SN, Ke Z, Ward AB, Lindesmith LC^#, Baric RS^#, Georgiou G^#

Proceedings of the National Academy of Sciences 123, e2603905123 (2026).

B cell imprinting in children impairs antibodies to the haemagglutinin stalk

Sun J^*, Jo G^*, Troxell CA, Fu Y, Hoezl R, Lv H, Abozeid HH, Teo QW, Pholcharee T, McGrath JJC, Changrob S, Nelson SA, Yasuhara A, Huang M, Zheng NY, Chervin JC, Li L, Fernández Quintero ML, Loeffler JR, Rodriguez AJ, Huang J, Swanson OM, Balmaseda A, Kuan G, Campredon L, Allen EK, Neumann G, Wu NC, Kawaoka Y, Krammer F, Mejias A, Ramilo O, Thomas PG, Gordon A, Ward AB, Han J, Wilson PC^#

Nature 653, 528–537 (2026).

✦ Author interview at BRIC Distinguished Korean Scientists

Childhood immunological imprinting of cross-subtype antibodies targeting the hemagglutinin head domain of influenza viruses

Li SH^*, Wang B^*, Jo G, Mikelov A, Atkinson RK, Le Sage V, Furey C, Ort JT, Ye N, Gang S, Shah R, Santos JJS, Röltgen K, Joshi SA, Lee JY, Pursell TA, Drapeau EM, Han J, Callear AP, Collman RG, Monto AS, Martin ET, Lakdawala SS, Ward AB, Wilson IA^#, Boyd SD^#, Hensley SE^#

Cell Host & Microbe 34, 873–887.e11 (2026).

Antiviral and anti-inflammatory effects of Tabamide A derivative, TA25, against human rhinovirus and multiple zoonotic viruses in vitro and in silico

Kim B, Ulzii AB, Lim T, Kim JW, Im WR, Rajoriya S, Natasha A, Misra D, Hennisa H, Kwag NY, Yoon D, Jo G, Park YB, Park J, Lee JT^*, Jeon SH^*, Kim WK^*

Scientific Reports 16, 20112 (2026).

Structural basis of broad protection against influenza virus by human antibodies targeting the neuraminidase active site via a recurring motif in CDR H3

Jo G, Yamayoshi S, Ma KM, Swanson O, Torres JL, Ferguson JA, Fernández Quintero ML, Huang J, Copps J, Rodriguez AJ, Steichen JM, Kawaoka Y, Han J^#, Ward AB^#

Nature Communications 16, 7067 (2025).

✤ Editors’ Highlights in Nature Communications, Microbiology and infectious diseases
✤ Featured in Trends in Microbiology — “On target: antibodies against the neuraminidase active site” (2025)
✦ Author interview at BRIC Distinguished Korean Scientists

HIV-1 envelope trimer vaccine induces sex-associated differences in antibody responses: a phase 1 clinical trial

Reiss EIMM, van der Straten K, Graus LTM, Grobben M, Vlaming KE, van der Veen AIP, Liesdek MH, Ozorowski G, Corcoran M, Gao H, Greene KM, Yates NL, Sawant S, Kerster G, Burger JA, Schonherr S, Cheeseman HM, Evans A, McFarlane LR, Tran AS, Torres JL, Lin RN, Jo G, Tolazzi M, Mundsperger P, Katinger D, Cupo A, Moore JP, Hurks R, Vogt L, Soeters MR, Kootstra NA, Scarlatti G, Tomaras GD, Montefiori DC, Karlsson Hedestam GB, Ward AB, Klouwens M, de Jong MD, Prins JM, Claireaux M, Geijtenbeek TBH, Shattock RJ, van Gils MJ, Sanders RW^#, de Bree GJ^#

Nature Communications 16, 10250 (2025).

Single-molecule fingerprinting of protein–drug interaction using a funneled biological nanopore

Jeong KB^*, Ryu M^*, Kim JS^*, Kim M, Yoo J, Jeong M, Oh S, Jo G, Lee SG, Kim HM, Lee MK^#, Chi SW^#

Nature Communications 14, 1461 (2023).

Structural insights into the clustering and activation of Tie2 receptor mediated by Tie2 agonistic antibody

Jo G^*, Bae J^*, Hong HJ, Han AR, Kim DK, Kim JA, Lee S, Koh GY^#, Kim HM^#

Nature Communications 12, 6287 (2021).

✦ Author interview at BRIC Distinguished Korean Scientists

Multivalent-interaction-driven assembly of discrete, flexible, and asymmetric supramolecular protein nano-prisms

Han S^*, Kim YN^*, Jo G, Kim YE, Kim HM, Choi JM, Jung Y^#

Angewandte Chemie International Edition 59, 23244–23251 (2020).

Generation and characterization of monoclonal antibodies to the Ogawa lipopolysaccharide of Vibrio cholerae O1 from a phage-displayed human synthetic Fab library

Kim D, Hong J, Choi Y, Han J, Kim SK, Jo G, Yoon JY, Chae H, Yoon H, Lee C, Hong HJ^#

Journal of Microbiology and Biotechnology 30, 1760–1768 (2020).

Generation of a human monoclonal antibody to cross-reactive material 197 (CRM197) and development of a sandwich ELISA for CRM197 conjugate vaccines

Kim D, Yoon H, Kim SK, Wi J, Chae H, Jo G, Yoon JY, Kim H, Lee C, Kim SH, Hong HJ^#

Journal of Microbiology and Biotechnology 28, 2113–2120 (2018).

Generation and characterization of a neutralizing human monoclonal antibody to hepatitis B virus PreS1 from a phage-displayed human synthetic Fab library

Jo G^*, Jeong MS^*, Wi J, Kim DH, Kim SK, Kim D, Yoon JY, Chae H, Kim KH, Hong HJ^#

Journal of Microbiology and Biotechnology 28, 1376–1383 (2018).

Generation of a monoclonal antibody that has reduced binding activity to VX-inactivated butyrylcholinesterase (BuChE) compared to BuChE by phage display

Yoon JY^*, Kim DH^*, Kim S, Kim D, Jo G, Shin MS, Yoo J, Kang HK, Kim MS, Kim YJ, Lee NT, Hong HJ^#, Kim YW^#

Biotechnology and Bioprocess Engineering 22, 114–119 (2017).